Simulation of Schizophrenia Tsukasa Okimura 1 , Kentaro Katahira 2 , Yoshihiko Kunisato 3 , Yuichi Yamashita 4 1Hasegawa Hospital 2Department of Cognitive and Psychological Sciences, Graduate School of Informatics, Nagoya University 3Department of Psychology, Senshu University 4Department of Functional Brain Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan Keyword: 計算論的精神医学 , 生成モデル , 生物物理学的モデル , ニューラルネットワークモデル , チャットボット , PARRY , computational psychiatry , generative model , biophysical model , neural network model , chatbot pp.771-783
Published Date 2019/7/1
DOI https://doi.org/10.11477/mf.1416201349
  • Abstract
  • Look Inside
  • Reference


There have been so many and various researches of schizophrenia since the early days of modern psychiatry, but the pathology remains unexplained, and the treatmens not established. One of the reasons is the complexity of a brain which makes it difficult to form a bridge between biological findings and symptoms. Computational psychiatry has been recently expected to overcome this difficulty. In the field, a brain is seen as an information-processing system, and the dynamics of a brain are expressed using mathematical models. In addition, mental disorders are expressed as changes including parameters in the models. Here, we introduce some studies conducted in Japan.

Copyright © 2019, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院