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Japanese

Clinical features and diagnosis of uveitis simulating Behçet's disease Kaoru Araki 1 , Yayoi Nakagawa 1 , Rei Tada 1 , Tetsuo Sasabe 1 , Masahito Ohji 1 , Yasuteru Haruta 1 , Takenosuke Yuasa 1 1Dept of Ophthalmnol Osaka Univ Med Sch pp.1065-1068
Published Date 1988/9/15
DOI https://doi.org/10.11477/mf.1410210510
  • Abstract
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We evaluated the clinical features, courses and laboratory findings in 24 patients with ocular symp-toms similar to Behçet's disease in the foregoing 5-year period. All the cases had none or one of extraocular involvement. The ocular findings in-cluded anterior uveitis, diffuse vitreous opacity, venous dilatation of the retina and hyperpermeable retinal venules similar to Behçet's disease. They belonged to either of three groups : hypopyon type, exudative type with retinal exudates, and non-specific type. Cases of exudative type were further divided into two subgroups. Cases in one subgroup manifested recurrent retinal exudates that charac-terize Behcet's disease and those in the other sub-group manifested occasional tiny nonspecific exudates. Almost all the cases that failed to mani-fest retinal exudates for one year were assigned to nonspecific type. HLA-A 26 was found in 6 out of 9 cases of exudative type, and HLA-DQw1 in 6 out of 9 cases of nonspecific type.

Behget's disease is characterized by recurrence and hyperreactivity of neutrophils. Cases with recurrent hypopyon or retinal exudates, therefore, were likely to be diagnosed as Behget's disease after other diseases were ruled out. Cases with infrequent noncharacteristic retinal exudates could not be diagnosed as Behget's disease due to lack of conclusive evidences. We ultimately diagnosed 8 cases in the series as Behcet's disease.

Rinsho Ganka (Jpn J Clin Ophthalr6ol) 42(9) : 1065-1068, 1988


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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