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60歳前後の女性にみられたウイルス性と思われる両眼性網膜ぶどう膜炎の3症例を報告した。3例とも前眼部の炎症は軽度で,隅角に結節があり,軽度ないし中等度のびまん性硝子体混濁がみられた。眼底には,赤道部から周辺部にかけて小円形の黄白色滲出斑が散在し,一部に網膜壊死様の融合した滲出斑が存在した。網膜動脈炎および静脈炎もあった。眼病変の推移は緩慢で徐々に軽快し,大量のステロイドとアシクロビルが有効であった。これらの症例の臨床症状および経過が他のウイルス性網膜ぶどう膜炎と類似しており,前房水の検索による結果も総合すると,単純ヘルペスウイルスの関与が疑われた。
We observed three cases of bilateral chorio-retinitis with strikingly characteristic features in common. All were females and were aged 58,59 and 60 years respectively. All the cases manifested mild signs of inflammation in the anterior segment,nod-ules in the chamber angle and mild to moderate diffuse vitreous opacity. Fundus lesions were char-acterized by small, round, yellowish-white exudates disseminated over the equator and the periphery. The exudates occasionally fused and simulated retinal necrosis. Occlusion of retinal artery and sheathing of retinal vein were also present. The retinal lesions gradually subsided after systemic treatment with corticosteroid and acyclovir in massive doses. Tests of serum and aqueous humor were suggestive of infection by herpes simplex virus.
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