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Japanese

Experimental Studies on the Toxicity of Blastcidin after Intraocular Administration. Miyako Ojima 1 1Department of Ophthalmology, School of Medicine, Tohoku University pp.39-48
Published Date 1967/1/15
DOI https://doi.org/10.11477/mf.1410203571
  • Abstract
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Rabbit experiments were conducted over the toxic nature of Blasticidin, which is a new antibiotic agent against the rice blasts and which has been found to cause ocular irritation after surface application. The present paper isintended as a continuation of an earlier one by the same author which appeared in Jap. J. Clin. Ophth. 18( 7 ) : 813-823, 1964.

0.01% Blasticidin solution, which had been found to be innocuous on external application, was injected either into the anterior chamber at the dose of 0.1ml or into the vitreous at the dose of 0.2ml. The clinical and pathological conditions were followed up to one month.


Copyright © 1967, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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