耳鼻咽喉科領域における新局所麻酔剤オスモカイン（hexylcaine）の使用経験

　最近米国に於て広く使用せられている新局所麻酔剤hexylcaine（米国：cyclaine，日本：osmocaine持田）は，1944年Cope及びHancockにより合成され，1948年Beyerらによつて効果が確認され，その後も総ゆる種類の局所麻酔に応用されて優秀な局所麻酔剤である事が知られるに至つた。その長所は，（1）麻酔効果が大で低濃度にて満足な麻酔効果が得られる。（2）効果の発現が早い。（3）持続時間が長い。（4）各種の麻酔に応用し得る。（5）毒性が低いので安全域値が広い。

　我々は持田製薬株式会社の御好意によりオスモヵイン（hexylcaine）を当科外来患者76例に使用する機会を得たので報告する。使用したオスモカインは，0.5％（浸潤麻酔用），1％（浸潤麻酔用）5％（表面麻酔用）溶液である。

　New anesthetic drug "Osmocaine" or hexylcaine was administered on 76 patient who were recieved minor operations of the nose and throat. Among these tonsillectomy was 31 cases. While 21 cases were operated under infiltration anesthesia utilizing 0.5% osmocaine, 10 cases with 1%. Dosis of solution was 15cc and 20cc respectively. The operations were perforemed without any pain excepting 2 cases using 0.5% solution, who complained slight pain and horseness.

　Deviatomy of 9 cases and conchotomy of 7 cases were performed with no complications under local anesthesia with 0.5% osmocaine. Polyps on the vocal cord was removed with indirect laryngoscopic technique under surface anesthesia with 5% osmocaine in 7 cases. The anesthetic effect of the drug were sufficient for supression of the laryngeal reflex.

　Maxillotomy of 7cases were performed under infiltration anesthesia with 20cc of 0.5% solution and the patients complained no pain. The drum membrane was anesthetized completely in 26 cases for the myringotomy and the simple puncture with the solution prepared as follows: 5% osmocaine 0.4cc, menthol 2.0cc, carbol 2.0 cc and alcohol 2.0 cc.