慢性副鼻腔炎に於ける形質細胞の發生について

　1．まえがき

　形質細胞の発生と機能については既に古くからいろいろの研究が行われている．しかし未だに明確な結論に達していない．最近，天野（1944）の超生体染色伸展固定法によつて外膜形質細胞系なる体系が唱えられ，ここに形質細胞が再び脚光を浴びるに至つた．振り返つて耳鼻咽喉科領域を見ると，特に上部氣道の慢性炎症及び腫瘍の際に形質組胞が多数に発生する事が報告されている．しかしその発生起源については未だ詳細な研究は見受けられない．

　私どもは慢性副鼻腔炎を材料として，形質細胞の起源を追求し，二三の興味ある結論を得たのでここに報告するものである．

Kitagawa made attempts to trace the origin of reticulo-endothelial cells in chronic nasal sinu-sitis. He classifies the diseased mucous membr-ane of nasal sinus into three types from histo-pathological manife stations the forms of which are edematous, infiltrated, and fibrous. The infil-trated type is found to occur in the least num-ber constituting 8 of 74 specimens examined. Presence of reticulo-endothelial cells were found most prevalent in the immediate surroun-dings of submucousal capillaries the bood sup-plyin region of tde mucous membranes; and, also in the deeper reticular structures but to a lesser extent. Transitional stages of reticuo-en-dothelial cells were observed to be separating from the cells of external wall of the capillaries and from cells of the reticular tissues. From these observations the author concludes that re-ticulo-endothelial cells arise for the greater part from external wall of the mucousal capillaries and to a certain extent from the cells of reticu-lar tissues beneath.