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A New Operational Method of Functional Neurosurgery Combining Micro-recording and MRI Stereotaxy for the Treatment of Parkinson's Disease Hiroyuki Nishimura 1 , Tatsuo Hirai 2 1Department of Neurosurgery, Kochi Medical School 2Department of Neurosurgery, Fujieda Heisei Memorial Hospital Keyword: Parkinson's disease , thalamotomy , MRI stereotaxy , micro-recording , thalamus , tremor pp.144-155
Published Date 1993/2/1
DOI https://doi.org/10.11477/mf.1406900444

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  • Abstract
  • Look Inside

We have developed a new operational method forstereotactic functional neurosurgery using MRI stereotaxy combined with microelectrode record-ing. MRI stereotaxy shows us the individual varia-tions of thalamic configurations. The tentative tar-get points were determined using the MRI stere-otaxy assisted software system which revised the distorsion of MRI images. Consequently, the accu-racy and safety of the microelectrode recordinsg were increased. This, in turn, increased the accu-racy of stereotactic thalamotomy while producing encouraging operational outcomes.

The effectiveness of stereotactic thalamotomy for Parkinson's disease was comfirmed by these excel-lent operaive results. The symptoms improved and the dosage of medications, including L-DOPA, de-cresed.

Furthermore, our results indicate that the dis-tributing area of deep sensory neurons in the thalamus extended more posteriorly and upward than previously expected. Therefore, the functional and anatomical similarity between the human and mon-key thalamus was reaffirmed. In this report, based on the above data, we reevaluated the neural mecha-nism of tremor and the role of stereotactic func-tional neurosurgery for Parkinson's disease.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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