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Assessment of Exercise Tolerance in Hypertrophic Cardiomyopathy Using Respiratory Compensation Point Takeshi Morita 1 , Satoshi Hirasaki 2 , Takashi Nakamura 3 , Jun Satomi 4 , Akiko Matsuo 5 , Akihiro Azuma 5 , Hiroki Sugihara 5 , Hajime Takamatsu 6 , Teruo Kitani 5 , Masao Nakagawa 5 1Department of Clinical Laboratory, Kyoto Interdisciplinary Research Institute Hospital of Community Medicine 2Department of Cardiology, Kyoto Prefectural Yosanoumi Hospital 3Department of Cardiology, Saiseikai Shiga Hospital 4The Faculty of Science and Engineering, Ritsumeikan University 5Second Department of Medicine, Kyoto Prefectural University of Medicine 6Internal Medicine, Kyoto Interdisciplinary Research Institute Hospital of Community Medicine Keyword: 肥大型心筋症 , 運動耐容能 , 呼吸性代償開始点 , hypertrophic cardiomyopathy , exercise tolerance , respiratory compensation point pp.827-833
Published Date 1999/8/15
DOI https://doi.org/10.11477/mf.1404901950

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  • Abstract
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 A patient with hypertrophic cardiomyopathy (HCM) can develop subjective symptoms on exercise because of cardiac dysfunction. Parameters such as peak oxygen uptake (peak VO2) and anaerobic threshold (AT) obtained by gas exchange analysis have been useful in objectively evaluating exercise tolerance. hi this study, we evaluated the usefulness of peak VO2, AT and a respiratory compensation point (RCP) in 25 patients with HCM (12 asymptomatic and 13 symptomatic) and 13 healthy volunteers.

 There were no differences in peak VO2, VO2 level at AT (VO2AT) or VO2 level at RCP (O2RCP) between healthy volunteers and the patients with asymptomatic HCM. There were also no differences in VO2AT between the healthy volunteers and the patients with symptomatic HCM, but peak VO2 and VO2RCP, in the symptomatic HCM group were lower than those of healthy volunteers and the patients with asymptomatic HCM. Peak VO2, had a stronger positive correlation with VO2RCP, than with . VO2AT.

 Exercise tolerance was maintained relatively well in patients with asymptomatic HCM, but decreased in HCM patients showing symptoms such as shortness of breath on exertion, suggesting the usefulness of RCP in objectively evaluating exercise tolerance.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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