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Comparative study of somatostatin receptor scintigraphy and pathological findings about neuro endocrine tumors(NETs) Noritoshi Kobayashi 1 1Department of Oncology Graduate School of Medicine, Yokohama City University Keyword: 神経内分泌腫瘍 , 111Inペンテトレオチドソマトスタチン受容体シンチグラフィ , ソマトスタチン受容体type 2a pp.267-272
Published Date 2019/3/10
DOI https://doi.org/10.18888/rp.0000000782
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The purpose of this study was to evaluate the clinical efficacy of 111In-pentetreotide somatostatin receptor scintigraphy(SRS)for detect of the lesion area in patients with neuroendocrine tumors(NETs). We compared the pathological findings of NETs with SRS. Forty one patients(18 males, 23 females, mean age 59 years, range 29-86)with NETs were retrospectively enrolled in this study. Primary sites were located in pancreas(n=26), stomach(n=1), small intestine(n=4), colon(n=6), other lesion(n=2), and unknown(n=2). According to WHO 2010 classification, Grad 1(G1)was seven cases, Grade 2(G2)was thirty one cases, and Grade 3(G3)was three cases. SRS showed positive findings in 6(86%)G1 cases, 29(94%)G2 cases, and 1(33%)G3 case. In 27 of 29 cases(93.1%), there was concordance of SSTR2a expression with SRS findings. The results of our study suggested that SRS could detect almost of all G1 and G2 NETs. SRS findings were high concordant with pathological findings.


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電子版ISSN 印刷版ISSN 0009-9252 金原出版

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