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Treatment of Malignant Tumors by Differential Hypothermia Ken SUGA 1 , Komei IKEDA 1 , Osamu YAMADA 1 , Takeo OHASHI 1 , Hideo Yo 1 , Ryosuke KATAGI 1 , Yoshinobu YOKOYAMA 1 , Minoru ARIMORI 1 , Hoji YOSHIZU 1 , Kazuo TABUCHI 1 , Hideo NOBUTO 1 , Akira NISHIMOTO 1 1Department of Neurological Surgery, Okayama University, Medical School Keyword: General bodyhypotemia , Normothemic tumor , Glioblastoma , Antitumor agents pp.51-57
Published Date 1973/7/10
DOI https://doi.org/10.11477/mf.1436200070
  • Abstract
  • Look Inside

Though many laboratory and clinical trials of tumor heating or cooling have been made for the treatment of intracranial tumors, the effects have been reported to be incomplete and unsatisfactory in most of the cases.

In 1965, Popovic et al. reported that differential hypothermia, to keep tumor normothermic under general body hypothermia, showed a more marked effect on the tumor in experimental animals.

The authors also confirmed that the transplanted cheek-pouch tumors of hamsters originally induced by adenovirus type 12 disappeared after 10-hr differential hypothermia treatment (D. H.).


Copyright © 1973, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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