Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
69歳,男性。腎細胞癌根治手術後17ヵ月目に脳転移を発見された。はじめに5-fluorou-racil(400 mg/日)を投与したが,転移巣は増大傾向を示した。そこで600 mg/日のmed-roxyprogesterone acetate(MPA)の経口投与を追加した。MPA投与4週間後に転移巣は縮小しはじめ,本療法開始2ヵ月後に完全寛解に達した。MPA大量投与による副作用は顔面紅潮と高血圧であった。本例は11ヵ月間完全寛解を維持し,健全である。
A 69-year-old man complaining of aphasia was found to have brain metastatic lesions from renal cell carcinoma which was radically resected 17 months ago. Although he was initially treated with 5- fluorouracil (400 mg/day), the metastatic tumors increased in size. Then medroxyprogesterone acetate (MPA), 600 mg daily, was added orally. Four weeks after the beginning of administration of MPA, the metastatic lesions began to regress on computer tomography and reached complete response 2 months after the treatment.
Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.