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はじめに
耳鼻科領域において,高アミラーゼ血症は流行性耳下腺炎等唾液腺疾患でよく経験されるが,1985年から1990年の間にわれわれは,膵臓に異常がなく,また唾液腺にも異常がない,原因不明の高アミラーゼ血症の2症例を経験した。
唾液腺型高アミラーゼ血症は,まず耳鼻咽喉科を受診するであろう事,および唾液腺型高アミラーゼ血症をすべて唾液腺疾患と考え過剰な検査が行われる可能性,さらに重大な疾患を放置する危険性,以上の3つの理由から,報告する。
Two cases of hyperamylasemia without pancre-atic disease or salivary gland disease were repor-ted. A 65-year-old male who was admitted as T.I.A. had persistent hyperamylasemia (salivary type). The result of examinations revealed that he had lung cancer (adenocarcinoma) producing amylase. A 49-year-old male with acute epiglotitis had hyperamylasemia without abdominal comp-laint. Isoamylase analysis showed non-pancreatic and non-salivary type. Serum amylase was eleva-ted but urine amylase was normal. Further examination indicated macroamylase to be an amylase linked to immunoglobulin IgA (κ, λ).
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