新生児角膜を用いた全層角膜移植の2例

Two cases of penetrating keratoplasty using donor cornea from a neonatal infant

（C2-3-6）　在胎期間36週6日で出生後12時間で死亡した無脳児の角膜を全層角膜移植の2例に使用した。1例は79歳女性の難治性角膜潰瘍に対ずる治療的角膜移植，1例は64歳男性の水疱性角膜症に対する光学的角膜移植である。移植角膜片は，成人のものよりも厚くて可塑性が大きく，縫合がやや困難であったが，特に問題はなかった。第2例では，手術10か月後の角膜曲率半径のK値が54.50Dであり，角膜がsteep化していた。角膜内皮細胞数は2,409／mm²であった。両症例とも病変の再発はなく，手術11か月の時点で移植片は透明である。

We performed penetrating keratoplasty in 2 eyes using the corneas from a newborn infant with anencephaly who died 12 hours after birth. It was used as therapeutic keratoplasty in a 79-year-old female with protracted corneal ulcer and as optical keratoplasty in a 64-year-old male with bullous keratopathy. The donor corneas were thicker and more flexible than adult donor cornea and required meticulous suturing. There were no further problems during surgery. The grafted cornea showed steepness with 54.50 diopers in K-value of the mean corneal curvature 10 months after surgery and corneal endothelial density of 2,409/mm² one month later. The postsurgical course has been uneventful in both cases with the grafted cornea staying transparent 11 months after surgery.