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高気圧酸素療法(OHP)の網膜静脈閉塞症に対する有効性を,非施行群と比較検討した。視力改善例はOHP施行群18眼中9眼(改善率50%),非施行群は18眼中3眼(改善率17%),黄斑浮腫改善例はOHP施行群16眼中13眼(改善率81%),非施行群は13眼中4眼(改善率31%)で,視力改善,黄斑浮腫改善ともに両群間に有意差(p<0.05,p<0.01)を認めた。また黄斑浮腫陽性例中視力改善例はOHP施行群で16眼中13眼(改善率81%),非施行群では13眼中4眼(改善率31%)で,両群間に有意差(p<0.01)を認めた。視力改善は,黄斑浮腫改善例に多く認められる傾向にあった。これよりOHPは本症に対して有効な治療法と考えられた。
We treated 18 eyes of retinal vein occlusions with hyperbaric oxygen therapy. The series comprised 12 eyes with central retinal vein occlusion and 6 eyes with branch retinal vein occlusion. Following an average of 20.3 sessions of treatment, visual acuity improved in 9 out of 18 treated eyes, 50%,and macular edema regressed in 13 out of 16 eyes, 81%. In another series of 18 eyes with retinal vein occlusions which served as control, visual acuity improved in 3 eyes, 17%, and macular edema re-gressed in 4 of 13 eyes, 31%. The differences between the treated and untreated groups were significant (p<0.05 for visual acuity and p<0.01 for macular edema). The follow-up period aver-aged 7 months in both series. Improvement in visual acuity was more pronounced in eyes with resolution of macular edema following hyperbaric oxygen therapy. The findings suggest the clinical useful-ness of hyperbaric oxygen therapy in the manage-ment of retinal vein occlusions.
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