脈絡膜腫瘍のインドシアニングリーン螢光眼底造影

Indocyanine green angiographic features of choroidal tumors

　脈絡膜腫瘍15例16眼にインドシアニングリーン螢光眼底造影（ICG造影）を行った。脈絡膜悪性黒色腫5例5眼は，メラニン色素がICG螢光をブロックして造影早期から晩期まで強い低螢光を示した。また，腫瘍の浸潤範囲を正確に示した。脈絡膜血管腫8例8眼は造影早期には腫瘍内に拡張した多数の腫瘍血管がみられ，造影中期から晩期にかけて旺盛な血管外漏出と螢光の貯留によって強い過螢光を示した。転移性脈絡膜腫瘍2例3眼は，造影早期から低螢光を示し脈絡膜血管の見え方は不明瞭であり，経過と共に組織染を示した。このように3つの脈絡膜腫瘍はそれぞれ特徴ある所見を示し，ICG造影は脈絡膜腫瘍の鑑別診断に極めて有用であった。

We evaluated 16 eyes of choroidal tumor using indocyanine green angiography. Five eyes of choroidal malignant melanoma showed pronounced hypofluorescence throughout the angiographic phases sharply defining the extent of the tumor. In 8 eyes of choroidal angioma, numerous dilated vessels were shown during the early angiographic phase. Intense hyperfluorescence developed during the middle to late angiographic phases due to extravasation and pooling of dye. In 3 eyes of metastatic choroidal tumor, the early angiographic phase was characterized by hypofluorescence and poor visibility of choroidal vessels. Tissue staining became more intense towards the late phase. The observed features were characteristic for each of the three types of choroidal tumor, suggesting the value of indocyanine green angiography in the differential diagnosis.