Japanese

Mutation in the mitochondrial gene in a case of diabetic retinopathy Miwa Hoshida 1 , Minoru Honda 1 , Sin-ichiro Kawano 1 , Sin Fujimori 2 1Dept of Ophthalmol, Teikyo Univ Sch of Med 2Dept of Internal Med Ⅱ, Teikyo Univ Sch of Med pp.827-830
Published Date 1996/5/15
DOI https://doi.org/10.11477/mf.1410904874
  • Abstract
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A 52-year-old slender and low-height woman presented with bilateral simple diabetic retinopathy and cystoid macular edema in the left eye. She had been diagnosed as diabetes mellitus 19 years before. Deafness set in 3 years before. Mitochondrial analysis showed mutation of adenine to guanine at mt DNA 3243. Cystoid macular edema resolved one month after laser photocoagulation. It appeared that the compromised function of retinal pigment epithelium, which is rich in mitochondria, might have been involved in the occurrence of cystoid macular edema.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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