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中心性輪紋状脈絡膜萎縮症と診断した6例12眼を検索した。インドシアニングリーン(indo—cyanine green:ICG)螢光造影の後期像では,黄斑部の萎縮病巣は,全例が低螢光を呈した。この所見はフルオレセイン螢光造影後期の組織染の有無とは無関係であった。フルオレセイン螢光造影でwindow defectがある萎縮病巣周囲の領域は,ICG螢光造影で6眼が境界鮮明な低螢光,6眼が斑状の低螢光を示した。4眼では,フルオレセイン螢光造影でのwindow defectの範囲よりもICG螢光造影での低螢光の範囲が広かった。ICG螢光造影は,本症での脈絡毛細管板レベルでの病巣の拡がりを確定するのに有用であった。
We examined 12 eyes of 6 patients with central areolar choroidal atrophy. The atrophic macular lesion showed hypofluorescence during the late phase of indocyanine green (ICG) angiography in all the eyes, suggesting atrophic choriocapillaris. This feature was independent of the presence or absence of tissue staining in late-phase fluorescein angiogram. Areas surrounding the atrophic lesion, which showed window defect by fluorescein angiography, showed well-demarcated hypofluorescence in 6 eyes and spotty hypo-fluorescence in 6 by ICG angiography. Hypofluorescent area by ICG angiography was more extensive than that by fluorescein angiography in 4 eyes. ICG angiography was thus useful in locating the extent of affected lesion at the level of choriocapillaris.
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