Characteristics of choroidal fluorescence in infrared fundus angiography Tomohiro Iida 1 , Kanemitsu Muraoka 1 , Norikazu Hagimura 1 , Syoji Kishi 1 , Takayuki Tanaka 1 1Dept of Ophthalmol, Gunma Univ Sch of Med pp.85-92
Published Date 1994/1/15
DOI https://doi.org/10.11477/mf.1410903606
  • Abstract
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We made in vitro and in vivo experiments on fluorescence from indocyanine green (ICG) and fluorescein sodium. Either solution was placed in two overlying flat glass chambers. The intensity of fluorescence from ICG (0.03mg/ml) increased linearly up to the depth of 400μm. The fluorescence from fluorescein (0.75mg/ml) remained constant independent of the depth of the solution. In clinical fundus angiography, ICG showed more intense fluorescence at the site of arteriovenous crossings, major choroidal vessels and choroidal angiomas. The choriocapillaris appeared as uniform background fluorescence. This feature allowed estimation of the patency of the choriocapillaris as distinct from deeper choroidal layers. Fluorescence by ICG angiography was thus dependent on the added sum of ICG contained in the area of observation, while that by fluorescein angiography tended to show the most superficial dye-containing layar because of saturation effect.

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