緑内障での乳頭周囲網脈絡膜萎縮と中心部視野障害の検討

Correlation of peripapillary chorioretinal atrophy with central visual field damage in glaucomas

　緑内障眼における乳頭周囲網脈絡膜萎縮（peripapillary chorioretinal atrophy：PPA）と中心部視野の関係を調べる目的で，初〜中期の正常眼圧緑内障（NTG）23例30眼，原発開放隅角緑内障（POAG）22例33眼における視野障害度とPPA／乳頭面積比（PPA／D比），乳頭縁／乳頭面積比（RD比）との関係を検討した。Humphrey自動視野計中心30-2プログラムのmean deviationはRD比により強く相関したが，中心10-2プログラムでのtotal deviationの平均値とは中心視野に対応したPPA／D比がより強い相関を示した。この結果から，PPAが中心部10°内視野障害程度，さらには緑内障の中心視力予後を予測しうる可能性があることが示唆された。

We investigated the correlation between peripapillary chorioretinal atrophy (PPA) and central visual field inpairment in 56 glaucomatous eyes. The series comprised 33 eyes with primary open angle glaucoma and 23 eyes with normal tension glaucoma. These eyes had mild to moderate visual field damage with the mean deviation (MD) given by STATPAC of -25 dB or greater. Higher correlation coefficients were present between MD of the central 30° visual field and rim area/disc ratio than PPA/disc ratio. The average of total deviation in the central 10° visual field showed a higher correlation with PPA/disc ratio in the temporal quadrant than the rim area/disc ratio in the same quadrant. The findings show that PPA is positively correlated with central visual field damage. The extent of PPA in glaucoma may serve as a prognostic factor for central visual field impairment.