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Herpes simplex virus genomes were detected in the aqueous humor in five cases of acute retinal necrosis Shuji Yamamoto 1,3 , Yoshikazu Shimomure 1 , Takenosuke Yuasa 1 , Shinji Danjo 1 , Yayoi Nakagawa 1 , Rei Tada 1 , Ryoko Yamamoto 2 , Kenichi Matsubara 3 1Dept of Ophthalmol, Osaka Univ Med Sch 2Dept of Ophthalmol, Kansai Med Univ 3Institute for Molecular and Cellular Biology, Osaka Univ pp.665-667
Published Date 1992/5/15
DOI https://doi.org/10.11477/mf.1410908475
  • Abstract
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We aspirated the aqueous humor from 7 eyes of 7patients with clinically suspected acute retinal necrosis. We used the polymerase chain reaction method to determine the etiological agents. Five of the 7 specimens were positive for amplified herpes simplex virus (HSV) and were negative for varicel-la-zoster virus (VZV) and cytomegalovirus (CMV). There is a high probability that HSV was involved in the pathogenesis of acute retinal ne-crosis in these 5 cases.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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