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Clinical features of acute retinal necrosis Kosuke Tsukamoto 1 , Riyo Uemoto 1 , Saori Ito 1 , Masaki Takeuchi 1 , Nobuhisa Mizuki 1 1Department of Ophthalmology, Yokohama City University School of Medicine pp.1427-1433
Published Date 2022/10/15
DOI https://doi.org/10.11477/mf.1410214534
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Abstract Purpose:To report clinical features of acute retinal necrosis(ARN).

Subjects and methods:Analysis of 44 eyes with ARN. This retrospective study was performed on 44 eyes of 39 patients diagnosed with ARN in the past 12 years at Department of Ophthalmology in Yokohama City University Hospital. Visual acuity, causative virus, and fluorescein angiography were evaluated.

Findings:The mean age was 53.0±17.4 years old. Visual acuity(logMAR)before treatment was 0.45±0.54, and after treatment was logMAR 0.38±0.69, no significant difference was detected. Eighteen eyes deteriorated to retinal detachment(RD)and causative viruses were varicella zoster virus(VZV)in 16 eyes, and herpes simplex virus in 2 eyes with a significantly higher incidence of VZV. Patient with RD also had significantly poorer posttreatment visual acuity(logMAR)of 0.71±0.69. Significant difference was detected between posttreatment visual acuity(logMAR)with vascular occlusion in retina(1.56±0.52)and without vascular occlusion(0.68±0.60). In the 26 eyes without RD, visual acuity(logMAR)after treatment(−0.03±0.10)was significantly better than that before treatment(0.35±0.44).

Concluions:In ARN, patients without RD can expect improvement in visual acuity with treatment. On the other hand, the patients with RD were more frequently affected by VZV and had a poorer visual prognosis. In addition, the visual acuity did not improve when vascular occlusion was observed before treatment.


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