Acute syphilitic posterior placoid chorioretinitisの2例

Two cases of acute syphilitic posterior placoid chorioretinitis

要約　目的：Acute syphilitic posterior placoid chorioretinitis（ASPPC）の2例の報告。

症例：第1例は右眼視力低下で受診した53歳男性。右眼黄斑部に黄白色病巣を認めた。梅毒血清反応が陽性であり，光干渉断層計，蛍光眼底造影の所見よりASPPCと診断し，アンピシリンの内服で眼所見は軽快した。第2例は左眼視力低下で受診した54歳男性。左眼黄斑部に黄白色病変と視神経乳頭発赤を認めた。梅毒血清反応，画像検査含めASPPCと診断した。ペニシリン点滴加療で眼所見は軽快した。

結論：眼底に黄白色病巣を認めた場合，ASPPCも鑑別に入れることが重要であると考えられた。

Abstract　Purpose：To report two cases of acute syphilitic posterior placoid chorioretinitis（ASPPC）.

Cases：A 53-year-old man presented with decreased vision in his right eye. There was a yellow-white lesion in the macular area. Serologic tests for syphilis were positive. Based on optical coherence tomography, fluorescein angiography and indocyanine green angiography findings we diagnosed ASPPC. After oral ampicillin treatment, the symptoms and ocular findings showed improvement. Another patient, a 54-year-old man, presented with decreased vision in his left eye. The optic disc in the left eye was hyperemic and there was a yellow-white lesion in the macular area. Based on serologic tests and multimodal imaging, we diagnosed ASPPC. After intravenous penicillin administration, the symptoms and ocular findings showed improvement.

Conclusion：It is important to make a prompt and accurate differential diagnosis of ASPPC when yellowish-white lesions are present in the macular area.