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Japanese

A pathomorphological study of the interaction between tumor and retinal pigment epithelial cells in retinoblastoma Masao Sagara 1 , Takuji Kanari 1 , Seiichi Kondo 2 1Department of Ophthalmology, Fukushima Medical College 2Div. of Ophthalmol., Ohara Gen. Hosp pp.144-150
Published Date 1984/2/15
DOI https://doi.org/10.11477/mf.1410209089
  • Abstract
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An electron microscopic investigation was con-ducted to study the interaction between tumor and retinal pigment epithelial cells in a 15-month-old girl's eye which was enucleated as treatment of unilateral retinoblastoma.

It was found that tumor cells intruded into the microvilli situated on the surface of retinal pigment epithelial cells and destroyed them. In addition, zonula adherens-like attachments between the tumor and retinal pigment epithelial cells, which have never been reported.


Copyright © 1984, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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