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Intraocular pressure,visual field and shape of optic disc after one year of latanoprost monotherapy Hiroko Ogata 1,2 , Nobuyuki Shoji 2 , Kimiya Shimizu 3 , Masao Takase 4 , Ako Arimoto 5 , Nobuko Nakazawa 6 , Masahiro Suzuki 3 , Toshiya Tomioka 1 1Dept of Ophthalmol,Musashino Red Cross Hosp 2Dept of Orthoptics and Vis Sci,Kitasato Univ Sch of Allied Health Sci 3Dept of Ophthalmol,Kitasato Univ Sch of Med 4Dept of Ophthalmol,Saitama Med Cent,Saitama Med Sch 5Yokohama Clin,Kanagawab Dental Univ 6Dept of Ophthalmol,Doaikinen Hosp pp.943-947
Published Date 2005/6/15
DOI https://doi.org/10.11477/mf.1410100296
  • Abstract
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A prospective study was made on 25 eyes of 15 cases of normal-tension glaucoma who had been treated by topical medication other than latanoprost. The medication was switched to latanoprost only. All the eyes were evaluated as to intraocular pressure(IOP),visual field and morphology of the optic disc before and one year after treatment with latanoprost. The ages of patients ranged from 42 to 82 years,average 68 years. The IOP averaged 15.1±2.6 mmHg before and 13.4±2.2 mmHg one year after treatment by latanoprost. The difference was significant(p<0.01). Visual field showed improved mean deviation. No changes had set in regarding parameters of optic disc morphology. The findings show that latanoprost induces hypotensive effect in normal-tension glaucoma and that it stabilizes the visual field and optic disc morphology for at least one year.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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