春季カタルの重症化に関与するアレルギー学的要因の多変量解析

Multivariance analysis of allergological factors for aggravation of vernal conjunctivitis

春季カタルの重症化に関与する全身アレルギー学的要因を患者26名について多変量解析法で検索した。重症度は数量化理論2類による臨床スコアで判定し，8つのアレルギー学的要因については，全因子を分類するための数量化理論3類を用いた。春季力タルの重症化には受動喫煙，血清総IgE値，発症年齢の順で関与が大きく，再発頻度とアレルギー疾患家族歴の関与は小さかった。4群に分けられた全因子のうち，受動喫煙が春季カタルの重症度と最も近縁であった。春季カタルの長期管理ではこれらの要因を考慮することが望ましい。

We evaluated the systemic allergological factors that contribute to the aggravation of vernal conjunctivitis in 26 patients. The severity was judged by clinical score. Eight major allergological factors were subjected to multivariance analysis using quantification study type 3. Aggravation of vernal conjunctivitis was most associated with passive smoking,followed by serum total IgE level and age of onset. It was less associated with frequency of recurrence and presence of allergic diseases in the family. Out of 4 groups of all factors,passive smoking was most associated with aggravation of vernal conjunctivitis. We advocate due attention to the above features in the long-term management of the disease.