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緒言
1957年Roughton and Forster1)が肺拡散能力(以下DL)を肺胞膜拡散能力(以下DM)と肺毛細管血量(以下Vc)との二つの因子に分離し測定する,原理ならびに方法を発表して以来,各種肺線維症の肺拡散を論じる場合,DMの測定は不可欠な課題となった。
しかし,これらの測定は,ガス分析機器,操作の繁雑などの点で一般的でなかった。
The gas chromatograph modified of Mura-kami's method has been used to analyze gases for simultaneous measurements of pul-monary membrane diffusing capacity (DMco), pulmonary capillary blood volume (Vc) and its flow (Qc) using the breath-holding tech-nique. The two basic columns, silica gel (30 cm in length) and 5 A molecular sieves (290 cm in length) were arranged in series on a dual-column chromatograph with an empty coiled column (8 m in length) to make a balance of both columns. Accurate repro-ducible analyses for C2H2, CO, Ne, CO2, O2 and N2 were obtained from a single 2ml gas sample.
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