耳鳴のニコチン酸療法小験

　緒言

　聴力問題が深く掘下げて研究され，長足の進歩を遂げている現在でも，耳鳴の成因或は本態に関しては吾人の知識は貧弱で，診療面でも一つの盲点となつておる。

　耳鳴の成因についての諸見解を大別すると大体2仮説に整理される。1つは感音系組織の異常興奮であるとするもので，Fowler^1），Atkinson^2），勝木^3）等によつて唱よられ，支持者も多い。他は伝音系組織異常説で，後藤（敏）^4）等によつて唱えられておる。

　Isono and associates find that, 100 ears selected at random affected with tinnites aurium, nicotinic acid administered intravenousely to be effective in the following manner:

　Thirteen per cent of this number appeared to be cured;8% with a marked improvement; 29% with some improvement; 3% with change in the character of tinnitus;47% with failure by no changes established in the tinnitus. Aside from tinnitus aurium caused by streptomycin therapy, the use of nicotinic acid appear to be effective in allaying of symptoms of this affection particularly among those caused by circulatory disturbances or those in which that are considered as cuase unknown. The effectivity appear to be influenced by duration nature and quality of the tinnitus. The arthors conclude that basic facts causing improvement in the affection may be due not only to the fact that nicotinic acid causes vasodilatation but also to some factors relative to nutrition that are still unknown.