咽喉頭結核「ストレプトマイシン」治療の臨床的組織学的経過

　緒言

　ストレフトマイシンが紹介されて以来，耳鼻科領域殊に喉頭結核に於て，卓効をうたわれて居るが，その大部分は臨床成績で，組織学的な観察をしているものは，比較的少い，相当進行した咽喉頭結核患者に，ストレプトマイシン治療を実施し臨床的，並びに組織学的観察を行い，相互の間に一定のずれを認めたので，その経過を報告し度い投与は最初1日1グラムを，毎日朝夕2回に臀筋内注射を行い漸次減量し，総量29.5グラムとし此の間4回，又ストレプトマイシン投与終了後1回計5回，潰瘍部より試験切片を採取組織学的観察を行うと共に，胸部における一般所見びにX線所見をも参考にした．

KODAI notes the relative rapidity with which symptoms of laryngo-pharyngeal tuberculosis are re-covered under streptomycin therapy. With microsc-opic observations a cure will be recognized but the progress of the condition to the stage of cure is ex-ccedingly a slow process. A gived case under pre-sent form of treatment may appear to be well under control for a cure bote. sujectively, and clinically but, biopsy ex-amination of specimens taken from the affected area even at that stage may show tubero ulous lesions in submucous structures. The author emphasizes thatone must not be over-influenced by an apparent cli-nical cures of the disease but the the-rapy with streptomycin should be continued until when a true cure is obtained.