ストレプトマイシンを使用せる喉頭結核症例に就て

　喉頭結核はストレプトマイシン（以下「ス」剤）が最も奏効する結核性疾患の一つである事は衆知の事であり，米國に於ては，喉頭結核の70〜80％は「ス」剤により，好轉せしめ得ると云はれておる．我々は最近まで其の恩惠に浴し得なかつたが，幸ひ咋年6月より我國に於ても「ス」剤の放出を受くるに到り，結核性疾患中最も悲惨な症状を呈する喉頭結核に大なる光明を與える事が出來る樣になつた．

　我々は今回，抗酸菌病研究所，宮城療養所に於て「ス」剤療法を行つた肺結核患者のうちで，喉頭結核を似ふた13例に就て，僅少例ではあるが，私見を述べて諸賢の御批判を乞ふ次第である．

Awadaguchi says the effect of streptomycin for relief of symptoms in laryngeal tuberculosis is discouraging when the lesion is present in the larynx proper simultaneously with advanced stages of pulmonary tuberculosis. His experie-nce covers 13 cases of this disease in which intramuscular injections of streptomycin were given in total doses ranging from 10 to 40 gra-ms at the rate of 1 gram per day. Streptomy-cin is found effective when it is given early in the course of disease in which tubercular lesions are found in the laryngopharynx and not in the larynx proper, that are ordinarily considered as blood-bourne infections. But, it is found to be most efficacious, regardless of the state of pul-monary conditions, when it is directed against the pain which might be the chief and only ca-use of difficulty of deglutition. Regarding tissue reactions towards the antibiotic, the author believes, it causes decrease of local inflamma-tory edema and encourages prolifertion of con-nective tissues.