Galactorrheaを伴った男性Acromegalyの1例

A Case of Male Acromegaly with Galactorrhea

I．はじめに

　下垂体腺腫のうちprolactin産生腫瘍女性例では，月経異常・乳汁分泌で発見される例が多い．一方末端肥大症を呈す男性腺腫例では，乳汁分泌を伴うものは稀であり^3,7,8）その臨床的意義も不明瞭である．今回われわれは，鞍内から海綿静脈洞，蝶形骨洞さらには節骨洞へと伸展したmixed GH-PRL adenomaで乳汁分泌を呈した男性末端肥大症例を経験した．男性下垂体腺腫例における乳汁分泌出現の機序を中心に若干の文献的考察を加えて報告する．

A 43-year-old man was admitted to our clinic with complaints of headache and nasal obstruction. He has noted increasing hand and foot size with decreasing libido and pollakiuria for ten years.

On admission, he showed galactorrhea. His visualsymptoms were slightly decreased. Endocrinological evaluation revealed high serum levels of GH and pro-lactin. A plain skull X-ray showed acromegalic features with remarkable destruction of dorsum sellae. A con-trast enhanced CT demonstrated an intrasellar high den-sity mass extending to the sphenoid sinus and the right ethmoidal sinus. A cerebral angiogram was normal.