脳外傷の研究（3）—外傷腦の血管系の組織學的研究

Study of the Traumatized Brain (3):Histologic Studies of the peripheral Blood Systems in Traumatized Brains

　私は既に發表した腦外傷の研究第1報^1）に於て腦の灰白質，白質の比重と水分量との關係から外傷腦に於ては水分量に富み比重大なる物質が腦實質内に進入する事を證明し，第2報^2）に於て腦實質の含鐵量を測定し外傷腦に於ては著明な充血があり，それは特に灰白質に於て著しく，その血液含有量は對照腦の約2倍に達する事を明にした。然らばこの血液は如何なる状態で如何なる場所に存在するのであろうか。これを明にする爲に私は腦血管系の組織學的研究を行つた。

　私の今迄の研究によると外傷腦に見られる充血は主として毛細血管系にあると推定せられるのでCampbell^3）等の發表したベンチヾン染色法（Be-nzidine Stain）と在來の組織學的検査法を併用し，この充血の状態を明にしようと試みた。本論文中で毛細血管と稱するのは西丸^4）の行つた分類法に從つたものである。

In the traumatized brains, by means of the benzidine staining after Campbell-Waki's me-thod, I demonstrated histologically the presence of functional vascular disturbances even in cases which no organic changes were found in the terminal vascular systems, used of normal patho-logical examinations. I observed marked conges-tion and hyperemia, and occasionally a picture of circulatory collapse, in the terminal portions of the vascular system, not only in the injured areas but also all over the traumatised brains. In the traumatized brains which survived sever-al days after injury, I found same findings as described above, but on the other hand there were some of the signs of atrophy, anemia and picture of so called "plaques jaunes" all of the brain.

From these findings I discussed the causes of serious general conditions and post-traumatic syndroms after the head injury and emphasized the funcitonal circulatory disturbances are the most important mechaism after the head injury.

Futher I touched on the rational treatment for acute closed head injuries.