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Studies on water and mineral metabolism in pulmonary emphysema, with special reference to sodium ion. Hamada KAZUO 1 , Yokoyama TSUYOSHI 1 1Department of Internal Medicine School of Medicine, Keio University pp.951-957
Published Date 1958/11/15
DOI https://doi.org/10.11477/mf.1404200696

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  • Abstract
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Water and mineral metabolism was studied in 31 cases with pulmonary emphsema having no complication.

1) Compared with normal mean, the average of sodium and potassium concentration of arterial plasma were slightly elevated, and chloride slightly decreased. TBW and ICF were slightly increased,but ECF and I S F unchanged and. CPV and CBV were decreased in the body, fluid.

2) Respiratory acidosis with anoxemia was observed in most of the cases, but in some cases, me-tabolic acidosis was found with or without respiratory acidosis, and 1 case showed respiratoy alka-losis.

3) Elevated arterial concentration of sodium was observed in cases with elevated arterial PCO2. Ho-wever, no correlation was seen between arterial blood pH and sodium concentration of arterial plasma. These results suggest that increase in sodium concentration of arterial plasma can be influenced by intracellular shift and renal regulation of body fluid.

4) Potassium concentration of arterial plasma was increased in cases with elevated arterial Pco2.

5) Positive correlation between sodium concentration of arterial plasma and pressure in pulmonary artery, pulmonary capillary and vena cava. was observed.

6) Negative correlation was noticed between sodium concentration of arterial plasma and ECF, ICF and CPV.

7) Influence of anoxia was also indicated by changes in sodium and potassium concentration of arterial plasma, but this effect is considered to be less than that of arterial Pco2.


Copyright © 1958, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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