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Endoscopy for Infectious Esophagitis Takashi Fujiwara 1 , Kumiko Momma 2 , Shinichiro Horiguchi 3 , Sawako Kuruma 1 , Go Kuwata 1 , Junko Fujiwara 2 , Taku Tabata 1 , Naoto Egawa 1 , Tsunekazu Hishima 3 , Naoki Yanagisawa 4 , Atsushi Ajisawa 4 , Misao Yoshida 5 1Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo 2Department of Endoscopy, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo 3Department of Pathology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo 4Department of Infectious Diseases, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo 5Foundation for Detection of Early Gastric Carcinoma, Tokyo Keyword: ヘルペス食道炎 , サイトメガロウイルス食道病変 , 食道カンジダ症 , HIV , 感染性食道炎 pp.1213-1224
Published Date 2011/7/25
DOI https://doi.org/10.11477/mf.1403102306

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 In order to clarify endoscopic characteristics of infectious esophagitis,62 cases with esophageal mucosal lesions caused by viral or candida infection among 46,816 cases underwent upper endoscopy from August 2004 to August 2010 were analyzed.

 Cause of infectious esophagitis were herpes virus,CMV(cytomegarovirus)and candida. 7 cases with herpetic esophagitis(0.015% in all upper endoscopies)had been diagnosed by pathological studies on endscopic biopsy specimens. Endoscopic findings of Herpetic esophagitis were multiple small and shallow ulcers in early stage. Thereafter, ulcers agglutinate each other and resulted in longitudinal or irregular shaped macular shallow ulcers edged with milky mucosa. 25 cases with CMV esophagitis could be classified to 2 types. Type A had punched-out ulcers and type B with shallow ulcers or erosions. We had observed treatment process in 15 cases with CMV esophagitis that got remission by anti-CMV drugs. The period to the remission and the depth of ulcers had close relationship. Type B ulcers had been epithelized in 2 weeks, and type A punch-out ulcers in 3 weeks or more. Grade II~IV candida esophagitis indicated for treatments were noted in 30 cases(0.064%). They had HIV infedtion in 11cases, cancer in 11(3 were post-operation), liver cirrhosis in 4, steroids user in 2, chronic mucocutaneous candidiases in 1 and GERD in 1. Only 1 cases had Grade IV esophagitis with esophageal stenosis.


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