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Small Early Poorly Differentiated Adenocarcinoma of the Colon and Rectum, Report of Two Cases Hiroyuki Kanao 1 , Shinji Tanaka 1 , Motomi Terasaki 1 , Koichi Nakadoi 1 , Sayaka Takata 1 , Shiro Oka 1 , Shigeto Yoshida 1 , Kazuaki Chayama 2 1Department of Endoscopy, Hiroshima University, Hiroshima, Japan 2Department of Gastroenterology and Metabolism, Hiroshima University, Hiroshima, Japan Keyword: 低分化腺癌 , 早期大腸癌 , 未分化型大腸癌 pp.1769-1776
Published Date 2010/10/25
DOI https://doi.org/10.11477/mf.1403102040

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 〔Case 1〕A 59-year-old-man. Abdominal CT revealed lymphnode swelling around the para-aorta. Colonoscopy revealed a type 0-Isp polyp in the ascending colon. It was 12mm in diameter. We performed EMR. Histological diagnosis was as follows : poorly differentiated adenocarcinoma ; with a depth of SM(2,500μm). The ly3, v2, lateral margin and vertical margin were negative. This patient died due to esophageal variceal rupture. As a result of the pathological autopsy, it was confirmed that this lesion was a colon submucosal cancer with lymph-node metastasis. 〔Case 2〕A 71-year-old-man. Colonoscopy revealed a type 0-Is polyp in the rectum, 10mm in diameter. We performed EMR. Histological diagnosis was as follows : poorly differentiated adenocarcinoma depth SM(4,000μm). The ly3, v0, lateral margin and the vertical margin were negative." Surgical resection was performed, and there was lymph node metastasis. This patient died of the peritonitis carcinomatosa 13 months later, despite the performance of chemotherapy. These cases showed the high malignant potential of poorly differentiated adenocarcinoma of the colon.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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