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要旨 患者は50歳代,女性.検診にて便潜血反応陽性となり,大腸内視鏡検査を施行された.盲腸に側方発育型大腸腫瘍(LST)を認め,精査のため入院となる.形態はLSTの非顆粒型で平坦隆起部に低分化腺癌を認め,回盲部切除術を施行する.病理は盲腸(C),adenocarcinoma,por2,sig>tub1,大きさ13×12mm,深達度pSM(粘膜筋板下端から2,000μm),ly2,v1,pN1であった.本例は,腫瘍の花弁状部が高分化管状腺癌,平坦隆起部が低分化腺癌と,異なる組織像を呈していた.拡大内視鏡所見にて,平坦隆起部に小さな点状所見を認め,低分化傾向を有する腫瘍と診断した.大腸の早期低分化腺癌において拡大内視鏡所見が診断,治療に有用であった症例を報告した.
A 50-year-old woman visited our hospital for further examination concerning positive fecal occult blood. Colonoscopy revealed a Type LST(laterally spreading tumor, non-granular type)lesion in the cecum, measuring 13mm in the largest diameter. A part of the flat elevated area mostly appeared to be poorly differentiated adenocarcinoma. Ileocecal resection was performed. This case is a very rare case with poorly differentiated early adenocarcinoma.
As for this example, the pseudo-depressed part of a tumor presented the histology of well differentiated adenocarcinoma, and the flat elevated parts were different from poorly differentiated adenocarcinoma. Magnifying endoscopy showed the form of small point findings in the flat elevated part and was diagnosed as poorly differentiated adenocarcinoma. In this case of early colonic poorly differentiated adenocarcinoma, magnifying endoscopic findings were reported to have been of use for both diagnosis and treatment.
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