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Early Poorly Differentiated Adenocarcinoma of the Colon, Report of a Case Minori Matsumoto 1 , Yutaka Saito 1 , Taku Sakamoto 1 , Takeshi Nakajima 1 , Takahisa Matsuda 1 , Ryouji Kushima 2 1National Cancer Center Hospital, Endoscopy Division, Tokyo 2National Cancer Center Hospital, Clinical Laboratory Division, Tokyo Keyword: 早期大腸癌 , 低分化腺癌 , 内視鏡診断 pp.1763-1768
Published Date 2010/10/25
DOI https://doi.org/10.11477/mf.1403102039
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 A 58-year-old woman consulted a previous hospital with a complaint of anorexia and weight loss. She underwent colonoscopy and a 15mm flat elevated lesion was detected in the transverse colon. She was referred to our institution for endoscopic treatment.

 Conventional colonoscopic examination revealed a flat elevated lesion with a slight depression in the transverse colon. Stretching folds and a reddish nodule were observed in the lesion. Magnifying NBI image showed an unusual capillary pattern with irregular capillary vessels. Crystal violet staining, using the magnifying view, identified a slight irregular small pit but a well demarcated area was not recognized. Finally, we estimated the depth of this lesion was SM(submucosal)slight and tried to perform diagnostic EMR, but the non-lifting sign was strongly positive in this lesion. We performed ESD(endoscopic submucosal dissection)to achieve en-bloc resection. Histologically, the cancer was almost completely mucosal, but the tumor was composed of moderately and poorly differentiated adenocarcinoma that infiltrated into the SM slight layer with lymphatic vessel invasion and severe fibrosis.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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