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Cronkhite-Canada症候群は消化管ポリポーシス,皮膚色素沈着,脱毛,爪萎縮などをきたすまれな非遺伝性疾患である。一般的に慢性下痢を主症状とし,蛋白漏出から低蛋白血症を呈することが多い。今回我々は下痢・体動困難を主訴に当院救急外来を受診し,CT検査にて胃巨大皺襞やびまん性の結腸壁肥厚を認め,精査の結果Cronkhite-Canada症候群と診断された1例を経験したので,若干の文献的考察を加えて報告する。
Cronkhite-Canada syndrome is a rare non-hereditary disease with gastrointestinal polyposis, diarrhea, hypoproteinemia, and skin pigmentation. We report a case in which giant gastric folds and diffuse colon wall thickening were confirmed by computed tomography. A woman in her 70 s visited our hospital with a complaint of chronic diarrhea. Her physical findings showed edema in her limbs, and blood tests showed hypoproteinemia. Gastric giant folds and diffuse colon wall thickening were confirmed by computed tomography. The pathology revealed Cronkhite-Canada syndrome, and sigmoid colon cancer was also pointed out at the same time. After treatment with prednisolone, the sigmoid colon cancer was resected.
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