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Studies on Destruction of Drugs by Ultrasonic Nebulization Hiroshi Kawaguchi 1 , Akio Ohara 2 , Yukio Fujiki 2 1Oto-Rhino-Laryngological Society of Kyoto 2Matsushita Science Center of Industrial Hygiene pp.617-622
Published Date 1981/9/20
DOI https://doi.org/10.11477/mf.1492209300
  • Abstract
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 Solutions of lincomycin, kanendomycin and neomyson were nebulized using an ultrasonic nebulizer for thirty minutes, but their physicochemical properties showed no changes.

 Poisonous gas in aerosol of lincomycin was foundto be dimethyl disulfid, and hydrogen sulfide by gas chromatography and mass spectrometry. Sulphuric compounds were not detected in aerosols of kanendomycin and neomyson.

 Aerosols produced by the ultrasonic nebulizer must be inhalated carefully because of hazardous effects of degenerated or destructed grugs.


Copyright © 1981, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 印刷版ISSN 0386-9679 医学書院

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