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Generation and migration of activated lymphocyte inducing experimental allergic encephalomyelitis in guinea pigs. Tokitada OHKAWA 1 1Department of Pathology, Murayama Annex, National Institute of Health pp.182-190
Published Date 1980/2/10
DOI https://doi.org/10.11477/mf.1431905151
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Abstract

After sensitization with neuroantigen to elicite experimental allergic encephalomyelitis (EAE), the generation and migration of activated lym-phocyte (AL), as recognized by Smetana's acid toluidin blue vital staining were followed accord-ing to the percentages of AL contained in the peripheral blood and the organs of immune and central nervous system (CNS) in guinea pigs.

In the brain, AL appeared from day 5 after sensitization prior to the onset of clinical sign of EAE and increased gradually till day 20 which is the last day of this experiment.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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