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Japanese

Radioimmunoassay of astroprotcin (an astrocyte-specific cercbroprotein) in cerebrospinal fluid and its clinical significance. Kazuyoshi MORIMOTO 1 , Toru HAYAKAWA 1 , Yukitaka USHIO 1 , Heitaro MOGAMI 1 , Takesada MORI 2 1Department of Neurosurgery, Osaka University Medical School 2Department of Surgery, Osaka University Medical School pp.75-81
Published Date 1978/2/10
DOI https://doi.org/10.11477/mf.1431904829
  • Abstract
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 In 1970, by immunofluorescence technique, Benda, Mori and Sweet demonstrated an unknown acidic cerebroprotein of fraction 10B (Bogoch) from a brain of Tay-Sachs' disease localized inglial cells in human glioma. Subsequently Mori (1970) confirmed this particular cerebroprotein to be specific to fibrillary astrocytes in normal brain as well as to astrocytoma cells in glioma, either human or rodent, and designated it as "astroprotein". Astroprotein has been proven to be identical to GFA protein, which was extracted later by Eng (1972) from gliosed brain tissues.


Copyright © 1978, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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