Japanese

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Yasuhiro Watanabe 1 1Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University Keyword: 筋萎縮性側索硬化症 , ALS , 前頭側頭型認知症 , FTD , 前頭側頭葉変性症 , FTLD , 原発性進行性失語症 , PPA , amyotrophic lateral sclerosis , frontotemporal dementia , frontotemporal lobar degeneration , primary progressive aphasia pp.1227-1235
Published Date 2019/11/1
DOI https://doi.org/10.11477/mf.1416201432
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Abstract

Amyotrophic lateral sclerosis (ALS) is often comorbid with frontotemporal dementia (FTD). Patients may exhibit language deficits as seen in progressive non-fluent aphasia (PNFA) or semantic dementia (SD). In behavioral variant FTD (bvFTD), cognitive impairments such as executive function, verbal fluency and language abnormalities are frequently seen, while apathy and disinhibition are major behavioral changes. Further, there are many ALS patients who do not fulfill the criteria for FTD but have mild cognitive and/or behavioral impairments. Appropriate evaluation of these conditions is necessary for non-pharmacological and pharmacological interventions.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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