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A Case of Flutamide-Induced Acute Cholestatic Hepatitis Masaki Sakurai 1 , Hiroshi Matsuura 1 , Atsushi Yamashita 2 , Tokuya Kondou 3 , Kiminobu Arima 4 Keyword: フルタミド , 肝機能障害 pp.851-853
Published Date 1998/10/20
DOI https://doi.org/10.11477/mf.1413904466
  • Abstract
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A 67 years old man with oral flutamide (375mg/day) after total prostatectomy (pT3, pN0, pMo) had normal liver function after 15 weeks of flutamide therapy. At 19 weeks he complained of general fatigue. He was admitted because of jaundice and severe liver injury at 20 weeks after fluta-mide therapy. At that time liver function tests showed total serum bilirubin 9.99 mg/dl, alaninamino transferase (ALT)968 IU/l, aspartate aminotransferase (AST)1,129 IU/l.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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