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37歳,男性。多数の肺転移腫瘍,後腹膜のバルキイ腫瘍を認め,ヒト絨毛性ゴナドトロピン122,000mlU/ml,β—ヒト絨毛性ゴナドトロピン1,200ng/ml,AFP3.4ng/mlであった。—方,精巣は触診上正常であったが,超音波検査で径12mmの低エコー像を示す腫瘍を認め,左精巣腫瘍と診断し,摘出した。組織は精上皮腫であった。化学療法により一時的に腫瘍マーカーが正常化し,後腹膜リンパ節郭清術を施行したが,その後に肺転移巣の増大,腰椎転移の出現がみられ,初診後33か月目に死亡した。
A 37-year-old man with a complaint of blood tinged sputum, had multiple lung metastatic tumors and retroperitoneal bulky tumors. Both testes were physically normal on palpa-tion, but scrotal sonography revealed a tumor, 12 mm in diameter, in the left testis. Histological diagnosis was seminoma. HCG, β-HCG and AFP levels were 122,000 mIU/ml, 12,000 ng/ml and 3.4ng/ml, respectively. After 4 cycles of BEP and 3 cycles of VIP chemotherapy, tumor markers decreased to normal levels and retroperitoneal lymphoadenectomy was performed.
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