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右精巣腫瘍にて高位除睾術を施行後に,右恥骨転移を認めた22歳,男性の患者に対し,シスプラチン,ビンブラスチン,ブレオマイシンの三者併用療法(PVB療法),放射線療法,シスプラチン,イフォスファミド,エトポシドの三者併用療法(VIP療法)および末梢血幹細胞輸血(PBSCT)併用超大量化学療法,さらに右恥骨切除術を施行したが寛解が得られず,パクリタクセル,イフォスファミド,シスプラチンの三者併用療法(TIP療法)を施行したところ,アルファフェトプロテイン(AFP)は正常化に至り,現在経過観察中である。
A 22-year-old man was admitted to our hospital with recurrence of non-seminomatous germ cell tumor on right pubic bone and liver. Resection of right pubic bone was performed after 9 cycles of cisplatin-based chemotherapy, PVB 7 cycles and VIP 2 cycles,and high-dose chemo-therapy, but complete response was not obtained. Therefore the patient was treated with 5 cycles of TIP therapy consist-ing of paclitaxel (175mg/m2 ,day1), ifosfamide (1.2g/m2 , day 2~4) and cisplatin (20mg/m2 , day 2~4). Then the serum concentration of α-phetoprotein (AFP) decreased from 1,088ng/ml to normal.
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