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Immune checkpoint inhibitor therapy for maxillary sinus metastasis of a renal cell carcinoma: A case report Atsumu Teramura 1 , Kazuo Yasuhara 1 , Toshiyuki Mukai 1 , Kento Kouda 1 , Shunichi Sugasawa 1 , Seikei Kan 1 1Department of Otorhinolaryngology, Takeda General Hospital pp.643-647
Published Date 2021/7/20
DOI https://doi.org/10.11477/mf.1411202766
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 Here, we report a case of maxillary sinus metastasis of a renal cell carcinoma treated with an immune checkpoint inhibitor. The patient was an 81-year-old man who presented with persistent right-sided epistaxis. A hemorrhagic tumor was found in the right middle nasal canal. Radiologic examination revealed that the mass had a strong contrast effect, destroying the hard palate. Pathologic examination showed that the tumor was consistent with a renal cell carcinoma metostasis. The patient was started on temsirolimus as the primary treatment, but became refractory, and nivolumab was introduced. Thirty-three months after initiation of nivolumab, although no immune-related adverse events (irAEs) occurred, the patient died of debility.


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電子版ISSN 1882-1316 印刷版ISSN 0914-3491 医学書院

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