Effect of peroral mecobalamin on the visual field defect in normal-tension glaucoma Yoshio Yamazaki 1 , Fukuko Hayamizu 1 , Takako Nakagami 1 , Chizuru Tanaka 1 , Mikako Yazaki 2 , Rieko Fukai 2 1Dept of Ophthalmol, Nihon Univ Sch of Med 2Eisai Cooperation Ltd pp.915-918
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905888
  • Abstract
  • Look Inside

We evaluated the effect of peroral mecobalamin on the visual field defect in 26 patients with normal-tension glaucoma (NTG) . Another series of 57 NTG patients served as control. Both groups showed similar features regarding visual field and other therapeutic modalities. The visual field was assessed using the retinal sensitivity in six divided sectors by Program 30-2 of Humphrey visual field analyzer. After 2 years of daily dosis of 1.5 mg of mecobalamin, the treated group showed improved retinal sensitivity. The control group showed significant reduction in retinal sensitivity in the superior and inferior papillomacular sector (p<0.02) and (p<0.05) respectively. The findings suggest the ef-fectiveness of oral mecobalamin on the visual function in NTG patients.

Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院