Effect of topical betaxolol on the intraocular pressure and respiratory function in patients with glaucoma or ocular hypertension Imako Takahashi 1 , Minoru Tanaka 1 , Yasuhiko Kobayashi 1 1Dept of Ophthalmol, Juntendo Univ Urayasu Hosp pp.911-914
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905887
  • Abstract
  • Look Inside

We treated 52 patients with ocular hypertension or various types of glaucoma by instillation of betaxolol. It was given as a first line medication in 35 patients. Reduction in intraocular pressure (TOP) averaged 3.6±2.7mmHg one month after medication (p<0.0001). In 11 patients who received betaxolol as additive therapy, it averaged 1.6±2.0mmHg (p=0.003). In 6 patients who received betaxolol as replacement, it averaged 0.5±1.0mmHg (p=0.103) . At 1, 3 and 6 months after onset of betaxolol, the IOP was significantly reduced in the group receiving as first line medication. We additionally measured the peak flow value as indicator of respiratory function in 21 patients. There was no difference in the peak flow value before and 3 months after betaxolol. The value was independent on the age or sex. The finding suggests that topical betaxolol does not induce untoward effects in aged patients.

Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院