A case of primary subconjunctival malignant lymphoma diagnosed by immunohistochemical and molecular biological analysis Masumi Watanabe 1 , Toshiro Shigemitsu 1 , Yoshinao Majima 1 , Yoshikazu Mizoguchi 2 , Toshikazu Matsui 3 1Dept of Ophthalmol, Fujita Health Univ Sch of Med 2Dept of Pathol, Fujita Health Univ Sch of Med 3Dept of Internal Med, Fujita Health Univ Sch of Med pp.895-898
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905883
  • Abstract
  • Look Inside

A 58-year-old woman presented with a tumor in her right eye. It was histologically diagnosed as diffuse malignant lymphoma of midium- sized cell type. Immunohistochemically, the tumor cells were positive for antimonoclonal antibody. Molecular biological analysis by Southern blot hydridization showed rearrangement of the bands of immunoglobulin heavy chain gene suggestive of monoclonal proliferation. No systemic abnormalities were present. The tumor was diagnosed as primary malignant lymphoma of medium-sized B cell type. Surgical excision, radiation and chemotherapy resulted in decrease of the tumor. There has been no local recurrence or metastasis during the one year's follow up.

Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院