A case of conjunctival malignant lymphoma diagnosed by genetic molecular analysis Yukako Nanjoh 1 , Kumiko Takamaki 2 , Chie Sotozono 2 , Koji Nishida 2 , Shigeru Kinoshita 2 1Dept of Ophthalmol, Kyoto Second Red Cross Hosp 2Dept of Ophthalmol, Kyoto Prefectural Univ of Med pp.1017-1020
Published Date 1997/5/15
DOI https://doi.org/10.11477/mf.1410908794
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A 58-year-old male presented with a salmon-pink tumor in the inferior fornix in his left eye. Biopsy showed diffuse proliferation of small to medium-sized lymphocytes with poor metamorphism, leading to the diagnosis of reactive lymphoid hyperplasia. Molecular biological analysis of another biopsied specimen showed immunoglobulin heavy-chain gene rearrangement and led to the definitive diagnosis as B-cell type malignant lymphoma. This case illustrates the usefulness of genetic molecular analysis in the differential diagnosis of lymphoproliferative disorders.

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