ベーチェット病患者の眼発作時における血液房水関門障害と眼圧変動

Impaired blood-aqueous barrier and intraocular pressure in Behet's disease

　ベーチェット病患者の眼発作時の血液房水関門障害と眼圧変動との関係を検討するため，虹彩毛様体炎発作を起こした本病患者19例を対象として眼圧と前房フレア値を測定した。フレア値（photon count／msec）が100以上の発作眼の平均眼圧は9.8mmHg，フレア値が100未満の発作眼は13.1mmHg，非発作時は14.1mmHg，非発作眼は14.6mmHgであり，フレア値が100以上の発作眼で他の群に比べ有意に眼圧が低下していた。さらに4mmHg以上の眼圧低下を示した発作回数の割合はフレア値が100以上の場合66.7％，100未満の場合24.1％であり，フレア値が100以上の発作の場合に眼圧低下のある発作回数が有意に多く認められた。

We evaluated the relationship between blood -aqueous barrier and intraocular pressure in 19 patients with Behçet's disease during attacks and remissions by quantitating the aqueous flare. The intraocular pressure averaged 9.8 mmHg when the aqueous flare was over 100 photon counts/msec during attacks. This value was significantly lower compared with 13.1 mmHg when the aqueous flare was less than 100 photon counts during attacks, 14. 1 mmHg during remissions and 14.6 mmHg in the opposite eyes of the affected eyes during attacks (p＜0.01). The intraocular pressure during attacks decreased by more than 4 mmHg in 67% when the aqueous flare was more than 100 photon counts and in 24% when it was less than 100 photon counts. The difference was significant (p＜0.01).